Now that casinos have spread in South Africa, Sun City is no longer the only gaming hotspot in the country, but it's still visually dramatic. Located two hours from Johannesburg, it's a sprawling complex of luxury hotels, restaurants and Vegas-style shows on the edge of Pilanesberg Game Reserve.

Tropical Kenyan archipelago Lamu makes for a blissful beach escape. Cobalt waters lap against the dramatic, rolling, white sand dunes that hem the island. Wade in to the refreshing waters and explore astounding snorkelling opportunities through coral reef that surrounds diminutive Kiwayu Island.

Mauritius is arguably Africa’s wealthiest destination, a tropical paradise with tons to do. Port Louis, the modern capital of this 38-mile by 29-mile island, is a bustling port with a revitalized waterfront and a busy market. But most visitors gravitate toward resort areas such as Mont Choisy, quiet Trou-aux-Biches and the more bustling Flic en Flac, popular with scuba divers. Rivière Noire is ideal for those looking for great deep-sea fishing.

It’s nicknamed the Eternal City for a reason. In Rome, you can drink from a street fountain fed by an ancient aqueduct. Or see the same profile on a statue in the Capitoline Museum and the guy making your cappuccino. (Which, of course, you know never to order after 11 am.) Rome is also a city of contrasts—what other place on earth could be home to both the Vatican and La Dolce Vita?