In Mancora, it’s all about the beach. Calm Pocitas Beach is a great place to soak up some sun, float serenely in a natural swimming pool or simply stroll the beautiful shoreline. Vichayito Beach is great for diving and kitesurfing, while the South Beach bustles with vendors, surfers and rowdy tourists. Book a guided adventure tour to visit nearby waterfalls and mud baths, or book a motorbike or horseback ride to explore the beaches and back roads.

The French-inspired Botanical Garden of Curitiba is one of the Brazilian city’s most popular attractions, its colorful flowers, ponds, paths, and art nouveau greenhouse creating a sweet-smelling fairyland. After a floral stroll, continue to explore Curituba’s lovely landscapes at Parque Estadual de Vila Velha and Parque Tanguá. Visit the Museu Oscar Niemeyer, a celebration of the architect’s bold, abstract works, then enjoy a performance at the marvelous Ópera de Arame, built to look like it’s fashioned out of wire.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."