It seems like every time of year is "in season" in Lenox, a small Berkshire town that has been a popular retreat since the 19th century. In summer, picnic on the lawn at Tanglewood, the Boston Symphony Orchestra's summer home. In fall, when foliage peaks, take to the hiking and biking paths of the Pleasant Valley Sanctuary to immerse yourself in the vibrant colours of the mountains. Winter visitors enjoy skiing at a number of resorts and cross-country trails, and in spring, hikers and golfers practice their pastimes in splendid settings. Rejuvenating treatments and pampering, at the well-known Cranwell Spa, are favored all year long.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

Basking in its 300 days of sunshine, Lake Tahoe is a haven for outdoor fun in every season. Swimming, kayaking and windsurfing are popular in the summer months, while epic snowfall makes for spectacular skiing in winter. For those who prefer indoor fun, there's plenty of that in Tahoe, too. With 24-hour casinos and a flashy nightlife scene, the area has a tangible Vegas vibe. A sprinkle of bling, if you will. Not surprising, since Lake Tahoe straddles the border between California and Nevada.