South Africa’s most popular tourist destination offers the urban thrills of Cape Town, its adjacent wine country and an aura of the rich political history of South Africa. The Overberg's perfect whale-watching perches provide excitement of a different nature. The Garden Route's lakes and forests and the Klein Karoo's ostrich-farming towns and vineyards present another take on the Cape. For extra kicks, try bungee jumping or cage-diving among Great Whites.

Knysna stands out on South Africa's famed Garden Route thanks to the sandstone cliffs that dramatically separate its tranquil lagoon from the pounding surf of the Indian Ocean. It's also home to the country's largest indigenous forest. Hop aboard a ferry for a ride through the scenic highlights. The Millwood Mines at Jubilee Creek, site of a major gold rush in 1885, provide a picturesque spot for a picnic. Be sure to try some local oysters during the renowned annual festival.

Imerovigli looks exactly as a Santorini village should: iconic whitewashed buildings with sapphire domes, narrow crisscrossing walking paths, epic sunsets. Set sail on a guided boat tour of nearby volcanic features or spend the day exploring the remains of Skaros, a 13th-century Venetian palace. Cap it all off with a simple but decadent meal of local delicacies.

The Mediterranean's biggest island is separated from the mainland by the Strait of Messina. A mountainous spot, Sicily's coast and its small islands sit at the foot of volcanoes, including Etna, Stromboli and Vulcano. The Greeks, Romans, Normans and Catalans all left their mark on the island in the form of Byzantine palaces, Gothic castles and Baroque flourishes in capital Palermo. Most larger towns offer interesting museums, but Etna and the Hellenic temples in Agrigento offer particularly unique sights.

To the first-time visitor, Palermo is a city of ever-changing character. An abundance of dusty museums, Arabian domes and flourishes of baroque splendor jostle with boisterous markets, chaotic traffic and oppressive summer heat. The Sicilian hotspot is a noisy, polluted, often dangerous, but always fascinating city. Don't miss marvels of Arab-Norman architecture, such as 12th-century Palazzo dei Normanni or San Giovanni degli Eremiti. Ask your hotel to arrange cabs and negotiate fares before setting off.