South Africa’s most popular tourist destination offers the urban thrills of Cape Town, its adjacent wine country and an aura of the rich political history of South Africa. The Overberg's perfect whale-watching perches provide excitement of a different nature. The Garden Route's lakes and forests and the Klein Karoo's ostrich-farming towns and vineyards present another take on the Cape. For extra kicks, try bungee jumping or cage-diving among Great Whites.

Knysna stands out on South Africa's famed Garden Route thanks to the sandstone cliffs that dramatically separate its tranquil lagoon from the pounding surf of the Indian Ocean. It's also home to the country's largest indigenous forest. Hop aboard a ferry for a ride through the scenic highlights. The Millwood Mines at Jubilee Creek, site of a major gold rush in 1885, provide a picturesque spot for a picnic. Be sure to try some local oysters during the renowned annual festival.

The caves of Plettenberg Bay are wrinkles in time, lined with ancient artifacts that date to the Middle Stone Age. Under the sun, Robberg, Central and Lookout beaches are pristine stretches of white sand, magnets for tourists, seagulls and dolphins, who bob playfully just off shore. Wildlife lovers will delight at the Birds of Eden aviary and Monkeyland. (How can you not have fun in a place called Monkeyland?)

Glamourous Santorini is deliciously different. Geographical newness is in part to thank. The island’s popular black volcanic Perissa and Kamari beaches are big draws, as is its arguably most famous Red Beach near Akrotiri (which is the place to go for archaeology buffs). Santorini curves round a giant lagoon in the Cyclades islands, offering stunning views from sky-high towns, eclectic cuisine, lovely galleries, thriving nightlife and excellent wines.

Relics ranging from ancient shrines to Venetian-style castles overlook swaths of golden sand beaches on Kos, a fertile island in Greece’s Dodecanese chain. Mega-resorts dominate the developed southern coast, while visitors looking for tranquility head to the quieter northern shores.